Positive LEEP margin was more common among women with a positive LEEP (53.7% see-and-treat vs 42.6% conventional) compared with a negative result (0% see-and-treat vs 3.7% conventional, P < 0.0001). I called the office Friday afternoon but did not hear back and have been a wreck all weekend. This represents a positive margin. Results Analysis of incisal margin condition of patients. During follow-up, 12 patients (6.6%) had residual/recurrent CIN 2+. ... Women who have negative co-testing results twice can repeat co-testing in three years and return to routine screening if results are negative 52). Once you've had a lumpectomy, you'll find out if your surgical margins were negative, positive, or close. My LEEP results were negative for HSIL! The American Society for Colposcopy and Cervical Pathology sponsored a consensus conference in 2001 to develop evidence-based guidelines for women with histologic abnormalities of … The results have shown that the patients with positive incisal margin and HPV had the highest deterioration rate. Also, avoid any heavy lifting or strenuous exercise for one week. One was lost to follow-up and the remaining 14 The inclusion criteria consisted of histologically verified CIN 2 and CIN 3 based on LEEP conization, and negative margins on pathological examinations in patients for whom both pre- and post-LEEP high-risk (HR) HPV test results (HCII) and pre-LEEP HR-HPV tests (HPV DNA chip assay) were available. Ectocervical or endocervical margins were negative after repeat LEEP conization in the majority of women, except for 2 patients (3.6%) with CIN 3 and positive ectocervical margins. Read more about a … study, 40% of relapses were in women with negative margin, but with persistent HPV 16 infection. Within the the endocervix there are endocervical glands. These studies have also been limited by single institutional reviews or small sample size. Ectocervical or endocervical margins were negative after repeat LEEP conization in the majority of women, except for 2 patients (3.6%) with CIN 3 and positive ectocervical margins. Download Citation | Involved LEEP Excision Margins as Predictor of Residual/Recurrent Disease in HIV-positive and HIV-negative Women in a Low-resource Setting | … Consecutive LEEP specimens with a CIN 2-3 diagnosis (and whose margins were negative for the … ... (0 replies) LEEP Results. combined the results from 18 studies published in the literature and found that 18% of patients with negative margins still had residual AIS, and 2% had cancer. The patients with a negative incisal margin and HPV exhibited the best prognosis. Patients had follow‐up at three month intervals with Pap smears and indicated colposcopy/biopsy. the abnormal cells extended to the margins of the sample. I cant make heads or tails out of this report! I got my LEEP results today. My results came back that my outside margins were clear/negative (in the front) but the inward margin, into the canal, was positive. One patient had EGD near or at the margin and was followed for 75 months without recurrence. It may be done in your doctor’s office, at a colposcopy clinic or at a hospital. Usually, a follow-up appointment will be recommended six months after your LEEP. Most concerning is the positive margins. One of 760 (0.13%) patients had double-negative results of both cytology and hrHPV. Obviously this means that they didn't get it all when they did the LEEP. In 19 cases of negative hrHPV, 18 available cytology reports were 5 HSIL, 4 ASC-US, 3 LSIL, 2 ASC-H, 2 AGC, 1 SCC, and 1 NILM. 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